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Fung, John

One or more keywords matched the following items that are connected to Fung, John

Item Type	Name
Concept	Mice, Inbred C3H
Academic Article	Use of MHC class I or II "knock out" mice to delineate the role of these molecules in acceptance/rejection of xenografts.
Academic Article	Prolongation of cardiac allograft survival by systemic administration of immature recipient dendritic cells deficient in NF-kappaB activity.
Academic Article	Mechanisms underlying the development of T-cell tolerance following interruption of signalling at the CD28/B7 and CD40/gp39 interface.
Academic Article	Second-set rejection of mouse liver allografts is dependent on radiation-sensitive nonparenchymal cells of graft bone marrow origin.
Academic Article	Phenotype and allostimulatory function of dendritic cells treated with antisense oligodeoxyribonucleotides targeting CD80 or CD86 mRNA.
Academic Article	Liver-derived DEC205+B220+CD19- dendritic cells regulate T cell responses.
Academic Article	Liver-derived dendritic cells induce donor-specific hyporesponsiveness: use of sponge implant as a cell transplant model.
Academic Article	Systemic administration of CTLA4-Ig or anti-CD40 ligand antibody inhibits second-set rejection of mouse liver allografts.
Academic Article	Differential effects of exogenous interleukin-10 on cardiac allograft survival: inhibition of rejection by recipient pretreatment reflects impaired host accessory cell function.
Academic Article	Increased apoptosis of immunoreactive host cells and augmented donor leukocyte chimerism, not sustained inhibition of B7 molecule expression are associated with prolonged cardiac allograft survival in mice preconditioned with immature donor dendritic cells plus anti-CD40L mAb.
Academic Article	Systemic administration of cellular interleukin-10 can exacerbate cardiac allograft rejection in mice.
Academic Article	Apoptosis of graft-infiltrating cytotoxic T cells: a mechanism underlying "split tolerance" in mouse liver transplantation.
Academic Article	Costimulatory molecule-deficient dendritic cell progenitors induce T cell hyporesponsiveness in vitro and prolong the survival of vascularized cardiac allografts.
Academic Article	The role of antibodies in liver graft-induced tolerance in mice: passive transfer of serum and effect of recipient B-cell depletion.
Academic Article	Transduction of dendritic cells with adenoviral vectors encoding CTLA4-Ig markedly reduces their allostimulatory activity.
Academic Article	Impact of donor MHC class I or class II antigen deficiency on first- and second-set rejection of mouse heart or liver allografts.
Academic Article	Cross-tolerance of recipient-derived transforming growth factor-beta dendritic cells.
Academic Article	Marked prolongation of cardiac allograft survival by dendritic cells genetically engineered with NF-kappa B oligodeoxyribonucleotide decoys and adenoviral vectors encoding CTLA4-Ig.
Academic Article	Transfection with genes encoding CTLA4Ig mediated by adenoassociated virus vectors prolongs survival of heart allografts.
Academic Article	Interleukin-2 and interleukin-12 mediate distinct effector mechanisms of liver allograft rejection.
Academic Article	Propagation of cells expressing donor phenotype (MHC class I, II and Y-chromosome) from the bone marrow of murine liver allograft recipients in response to GM-CSF in vitro.
Academic Article	Blockade of tryptophan catabolism prevents spontaneous tolerogenicity of liver allografts.
Academic Article	Neutralization of IL-12 reverses rejection of mouse liver allografts from Flt3-ligand-treated donors and is associated with suppression of both cellular and humoral responses.
Academic Article	Prolonged survival of heart allografts transduced with AAV-CTLA4Ig.
Academic Article	Combined blockade of CD28/B7 and CD40/CD40L costimulatory pathways prevents the onset of chronic rejection.
Academic Article	Prevention of diabetes in NOD mice by administration of dendritic cells deficient in nuclear transcription factor-kappaB activity.
Academic Article	Blockade of the CD28/B7 and CD40/CD40L costimulatory pathways does not ameliorate chronic rejection in a mouse aortic allograft model of direct antigen presentation.
Academic Article	Administration of antisense oligodeoxyribonucleotides targeting NF-kappaB prolongs allograft survival via suppression of cytotoxicity.
Academic Article	Apoptosis within spontaneously accepted mouse liver allografts: evidence for deletion of cytotoxic T cells and implications for tolerance induction.
Academic Article	Administration of dendritic cells transduced with antisense oligodeoxyribonucleotides targeting CD80 or CD86 prolongs allograft survival.
Academic Article	Successful hamster-to-rat liver xenotransplantation under FK506 immunosuppression induces unresponsiveness to hamster heart and skin.
Academic Article	Abrogation of chronic rejection in a murine model of aortic allotransplantation by prior induction of donor-specific tolerance.
Academic Article	Il-12 antagonism enhances apoptotic death of T cells within hepatic allografts from Flt3 ligand-treated donors and promotes graft acceptance.
Academic Article	Blockade of the CD40-CD40 ligand pathway potentiates the capacity of donor-derived dendritic cell progenitors to induce long-term cardiac allograft survival.
Academic Article	Mechanistic insights into impaired dendritic cell function by rapamycin: inhibition of Jak2/Stat4 signaling pathway.
Academic Article	Suppression of alloreactive T-cell activation by murine liver F4/80+ accessory cells and kinetics of intrahepatic F4/80+ cells following liver transplantation.
Academic Article	Donor pretreatment with Flt-3 ligand augments antidonor cytotoxic T lymphocyte, natural killer, and lymphokine-activated killer cell activities within liver allografts and alters the pattern of intragraft apoptotic activity.
Academic Article	Application of recipient-derived dendritic cells to induce donor-specific T-cell hyporesponsiveness.
Academic Article	Split tolerance induced by orthotopic liver transplantation in mice.
Academic Article	Recipient pretreatment with mammalian IL-10 prolongs mouse cardiac allograft survival by inhibition of anti-donor T cell responses.
Academic Article	Contrasting effects of myeloid dendritic cells transduced with an adenoviral vector encoding interleukin-10 on organ allograft and tumour rejection.
Academic Article	Hepatocytes and liver nonparenchymal cells induce apoptosis in activated T cells.
Academic Article	Enhancement of dendritic cell tolerogenicity by genetic modification using adenoviral vectors encoding cDNA for TGF beta 1.
Academic Article	Patterns of inflammatory vascular endothelial changes in murine liver grafts.
Academic Article	Growth of donor-derived dendritic cells from the bone marrow of murine liver allograft recipients in response to granulocyte/macrophage colony-stimulating factor.
Academic Article	Prevention of chronic rejection in mouse aortic allografts by combined treatment with CTLA4-Ig and anti-CD40 ligand monoclonal antibody.
Academic Article	Interferon-gamma induced expression of MHC antigens facilitates identification of donor cells in chimeric transplant recipients.
Academic Article	Systemic administration of anti-interleukin-10 antibody prolongs organ allograft survival in normal and presensitized recipients.
Academic Article	Prevention of T-cell activation by rhCTLA4-Ig and anti-CD40L monoclonal antibody results in indefinite islet allograft survival.
Academic Article	Treatment with CTLA4-Ig inhibits rejection of liver allografts from FIt3-ligand-treated donors.
Academic Article	Inhibition of IL-12 signaling Stat4/IFN-gamma pathway by rapamycin is associated with impaired dendritic [correction of dendritc] cell function.
Academic Article	Inhibition of T-cell responses by hepatic stellate cells via B7-H1-mediated T-cell apoptosis in mice.
Academic Article	Marked mitigation of transplant vascular sclerosis in FasLgld (CD95L) mutant recipients. The role of alloantibodies in the development of chronic rejection.
Academic Article	Presentation of MHC-disparate donor antigens predominantly by the indirect pathway results in the development of posttransplant vasculopathy: salutary effects of perioperative costimulatory blockade.
Academic Article	Hamster-to-rat liver xenografts protect extrahepatic organs from rejection.
Academic Article	Distinct response of liver myeloid dendritic cells to endotoxin is mediated by IL-27.
Academic Article	Mouse liver transplantation tolerance: the role of hepatocytes and nonparenchymal cells.
Academic Article	Prevention and restoration of second-set liver allograft rejection in presensitized mice: the role of "passenger" leukocytes, donor major histocompatibility complex antigens, and host cytotoxic effector mechanisms.
Academic Article	High-dose cellular IL-10 exacerbates rejection and reverses effects of cyclosporine and tacrolimus in Mouse cardiac transplantation.
Academic Article	In vitro propagation and homing of liver-derived dendritic cell progenitors to lymphoid tissues of allogeneic recipients. Implications for the establishment and maintenance of donor cell chimerism following liver transplantation.

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Mice Inbred C3H